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Antigenic Specificity | TLR |
Clone | monoclonal |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | WB, FuncS, |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Human Anti-TLR Recombinant Antibody (clone mAb 12). Recombinant Human Antibody (mAb 12) is capable of binding to TLR, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-TLR mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-TLR proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody binds an epitope that overlaps the C-terminal dsRNA binding site and blocks the interaction of TLR3ecd with dsRNA, thus directly antagonizing TLR3 signaling through inhibition of SU formation. |
Immunogen | Human Toll-like receptors |
Other Names | TLRs; Toll-like receptors |
Gene, Accession # | n/a |
Catalog # | PABL-724 |
Price | please inquire |
Order / More Info | TLR Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |