TLR Antibody from CREATIVE BIOLABS, INC.

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Antigenic SpecificityTLR
Clonemonoclonal
Host SpeciesRecombinant Human
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Sizen/a
Concentrationn/a
ApplicationsWB, FuncS,
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DescriptionHuman Anti-TLR Recombinant Antibody (clone mAb 12). Recombinant Human Antibody (mAb 12) is capable of binding to TLR, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-TLR mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-TLR proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody binds an epitope that overlaps the C-terminal dsRNA binding site and blocks the interaction of TLR3ecd with dsRNA, thus directly antagonizing TLR3 signaling through inhibition of SU formation.
ImmunogenHuman Toll-like receptors
Other NamesTLRs; Toll-like receptors
Gene, Accession #n/a
Catalog #PABL-724
Priceplease inquire
Order / More InfoTLR Antibody from CREATIVE BIOLABS, INC.
Product Specific Referencesn/a
CREATIVE BIOLABS, INC.
CREATIVE BIOLABS, INC.
CREATIVE BIOLABS, INC.
Suite 203
17 Ramsey Road
Shirley NY 11967
P: 1-631-416-1478
F: 1-631-207-8356

info@creative-biolabs.com

http://www.creative-biolabs.com

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