DNMT1 + SHH (bispecific) Antibody from CREATIVE BIOLABS, INC.
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| Antigenic Specificity | DNMT1 + SHH (bispecific) |
| Clone | monoclonal |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | n/a |
| Format | bispecific |
| Size | n/a |
| Concentration | n/a |
| Applications | FuncS; Promising therapeutic agent; |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recombinant Human Anti-DNMT1 x Anti-SHH Bispecific Antibody (Tandem scFv). Recombinant Anti-DNMT1 x Anti-SHH Bispecific Antibody (Tandem scFv) is designed to be expressed as a scFv from an anti-DNMT1 antibody variable domains fused with a scFv from an anti-SHH antibody variable domains. It contains a His-tag at the C/N terminus for affinity purification. The BsAb exits as monomer in reducing and non-reducing conditions. This BsAb can bind two factors simultaneously, block Hedgehog binding to PTCH, downregulate of DNMT1 and block DNA methylation. It is designed for the research of Hormone refractory breast cancer (HRBC) therapy. |
| Immunogen | n/a |
| Other Names | AIM; DNMT; MCMT; CXXC9; HSN1E; ADCADN; DNA methyltransferase 1; DNMT1 |
| Gene, Accession # | UniProt: I6L9H2 |
| Catalog # | BSFV-H316 |
| Price | please inquire |
| Order / More Info | DNMT1 + SHH (bispecific) Antibody from CREATIVE BIOLABS, INC. |
| Product Specific References | n/a |
CREATIVE BIOLABS, INC.
CREATIVE BIOLABS, INC.
Suite 203
17 Ramsey Road
Shirley NY 11967
P: 1-631-416-1478
F: 1-631-207-8356
info@creative-biolabs.com
http://www.creative-biolabs.com
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