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Antigenic Specificity | CCL16 (immunotoxin) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | ricin conjugate |
Size | n/a |
Concentration | n/a |
Applications | Cytotoxicity assay, Function study, |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-CCL16 immunotoxin FD441.8 (IgG)-RTA. This immunotoxin was achieved by conjugating/fusing the Anti-CCL16 monoclonal antibody to ricin toxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to CCL16 positive cells. Then the ricin A chain is incorporated into the cell by receptor-mediated endocytosis, blocking ribosomal protein synthesis and ultimately leading to cell death. It was designed for treatment of Graft-versus-host disease (GVHD). |
Immunogen | n/a |
Other Names | CCL16; chemokine (C-C motif) ligand 16; LEC; LMC; NCC4; CKb12; HCC-4; LCC-1; Mtn-1; NCC-4; SCYL4; ILINCK; SCYA16; C-C motif chemokine 16; monotactin-1; chemokine LEC; new CC chemokine 4; liver CC chemokine-1; IL-10-inducible chemokine; liver-expressed chemokine; small-inducible cytokine A16; lymphocyte and monocyte chemoattractant; small inducible cytokine subfamily A (Cys-Cys), member 16; Deglycosylated ricin A chain; Ricin A chain; Ricin A; Ricin; RTA; RT; RA; dgRTA; dgRA; dgA |
Gene, Accession # | UniProt: O15467 |
Catalog # | AGTO-G075R |
Price | please inquire |
Order / More Info | CCL16 (immunotoxin) Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |