ECD Antibody from CREATIVE BIOLABS, INC.

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Antigenic SpecificityECD
Clonemonoclonal
Host SpeciesRecombinant Human
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Sizen/a
Concentrationn/a
ApplicationsELISA, WB, FuncS,
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DescriptionHuman Anti-ECD Recombinant Antibody (clone mAb23). Recombinant Human Antibody (mAb23) is capable of binding to ECD, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-ECD mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-ECD proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody blocks glucagon binding and inhibits basal receptor activity, indicating that it is an inverse agonist and that the ECD can negatively regulate receptor activity independent of ligand binding.
ImmunogenHuman ecdysoneless homolog (Drosophila)
Other NamesECD; ecdysoneless homolog (Drosophila); GCR2; HSGT1; protein SGT1; suppressor of GCR2; protein ecdysoneless homolog; suppressor of S. cerevisiae gcr2;
Gene, Accession #UniProt: O95905
Catalog #PABL-460
Priceplease inquire
Order / More InfoECD Antibody from CREATIVE BIOLABS, INC.
Product Specific Referencesn/a
CREATIVE BIOLABS, INC.
CREATIVE BIOLABS, INC.
CREATIVE BIOLABS, INC.
Suite 203
17 Ramsey Road
Shirley NY 11967
P: 1-631-416-1478
F: 1-631-207-8356

info@creative-biolabs.com

http://www.creative-biolabs.com

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