Edit |   |
---|---|
Antigenic Specificity | CD89 + EGFR (bispecific) |
Clone | monoclonal |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | n/a |
Format | bispecific |
Size | n/a |
Concentration | n/a |
Applications | FuncS; Promising therapeutic agent; |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Anti-CD89 x Anti-EGFR Bispecific Antibody (Fab-IgG). Recombinant Anti-CD89 x Anti-EGFR Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can retarget macrophages to tumor cells. It is designed for the research of Head and neck cancer; Colorectal cancer (CRC); Glioblastoma multiforme (GBM); Squamous cancer; Non-small cell lung cancer (NSCLC); Solid tumors therapy. |
Immunogen | n/a |
Other Names | FcαRI; FCAR; Fc fragment of IgA, receptor for; CD89; FcalphaRI; immunoglobulin alpha Fc receptor; Fc alpha receptor |
Gene, Accession # | UniProt: P24071 |
Catalog # | FABIG-132 |
Price | please inquire |
Order / More Info | CD89 + EGFR (bispecific) Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |