S. aureus Hla Antibody from CREATIVE BIOLABS, INC.
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| Antigenic Specificity | S. aureus Hla |
| Clone | monoclonal |
| Host Species | Recombinant Human |
| Reactive Species | S. aureus |
| Isotype | n/a |
| Format | unconjugated |
| Size | n/a |
| Concentration | n/a |
| Applications | BL, |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recombinant Human Anti-S. aureus Hla Antibody (MEDI4893). Recombinant Human Antibody (MEDI4893) is capable of binding to S. aureus Hla, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-S. aureus Hla mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-S. aureus Hla proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. MEDI4893 recognizes a novel epitope in the so-called "rim" domain of AT and exerts its neutralizing effect through a dual mechanism. In particular, MEDI4893 not only sterically blocks binding of AT to its cell receptor but also prevents it from adopting a lytic heptameric trans-membrane conformation. |
| Immunogen | S. aureus alpha-hemolysin |
| Other Names | Hla; alpha-hemolysin; Alpha-toxin; Staphylococcus aureus alpha toxin |
| Gene, Accession # | n/a |
| Catalog # | PABL-396 |
| Price | please inquire |
| Order / More Info | S. aureus Hla Antibody from CREATIVE BIOLABS, INC. |
| Product Specific References | n/a |
CREATIVE BIOLABS, INC.
CREATIVE BIOLABS, INC.
Suite 203
17 Ramsey Road
Shirley NY 11967
P: 1-631-416-1478
F: 1-631-207-8356
info@creative-biolabs.com
http://www.creative-biolabs.com
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