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Antigenic Specificity | CD28 + EGFR (bispecific) |
Clone | monoclonal |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | n/a |
Format | bispecific |
Size | n/a |
Concentration | n/a |
Applications | FuncS; Promising therapeutic agent; |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Human Anti-CD28 x Human Anti-EGFR Bispecific Antibody (Minibody). Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Minibody) is designed to be expressed as the anti-CD28 scFv fused to N-terminus of Knob-CH3 domain and the anti-EGFR scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can retarget T cells to tumor cells. It is designed for the research of Head and neck cancer; Colorectal cancer (CRC); Glioblastoma multiforme (GBM); Squamous cancer; Glioblastoma; Medulloblastoma; Non-small cell lung cancer (NSCLC); Renal cell cancer (RCC); Solid tumors therapy. |
Immunogen | n/a |
Other Names | CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen |
Gene, Accession # | UniProt: P10747 |
Catalog # | MiniB-H234 |
Price | please inquire |
Order / More Info | CD28 + EGFR (bispecific) Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |