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Antigenic Specificity | CD18 |
Clone | monoclonal |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | FC, |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Human Anti-CD18 Recombinant Antibody (clone H52). Recombinant Humanized Antibody (H52) is capable of binding to CD18, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-CD18 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-CD18 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. The humanization of the anti-CD18 antibody H52 was hampered by not appreciating the possibilitythat residues in the C-terminal part of CDR-H2could be important in antigen binding. |
Immunogen | Human integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
Other Names | ITGB2; integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1; integrin beta-2; integrin beta chain, beta 2; complement receptor C3 beta-subunit; leukocyte cell adhesion molecule CD18; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor) |
Gene, Accession # | UniProt: B4E0R1 |
Catalog # | PABZ-019 |
Price | please inquire |
Order / More Info | CD18 Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |