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Antigenic Specificity | CD11A |
Clone | monoclonal |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | Neut, ELISA, IF, IP, FuncS, FC, WB, |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Human CD11A Recombinant Antibody (Efalizumab). Recombinant monoclonal antibody to Human CD11A. Efalizumab (trade name Raptiva, Genentech, Merck Serono) is a formerly available medication designed to treat autoimmune diseases, originally marketed to treat psoriasis. As implied by the suffix -zumab, it is a recombinant humanized monoclonal antibody administered once weekly by subcutaneous injection. Efalizumab binds to the CD11a subunit of lymphocyte function-associated antigen 1 and acts as an immunosuppressant by inhibiting lymphocyte activation and cell migration out of blood vessels into tissues. Efalizumab was associated with fatal brain infections and was withdrawn from the market in 2009. |
Immunogen | The details of the immunogen for this antibody are not available. |
Other Names | Efalizumab;raptiva;214745-43-4;hu1124;DB00095ITGAL;integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1;alpha polypeptide);CD11A;integrin alpha-L;LFA 1;LFA-1A;LFA-1 alpha;integrin gene promoter;CD11 antigen-like family member |
Gene, Accession # | UniProt: P20701 |
Catalog # | TAB-024 |
Price | please inquire |
Order / More Info | CD11A Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |