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Antigenic Specificity | HER3 + IGF1R (bispecific) |
Clone | monoclonal |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | n/a |
Format | bispecific |
Size | n/a |
Concentration | n/a |
Applications | FuncS; Promising therapeutic agent; |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Human Anti-HER3 x Anti-IGF1R Bispecific Antibody (Fab-IgG). Recombinant Anti-HER3 x Anti-IGF1R Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can bind and inactivate two receptors simultaneously. It is designed for the research of Pancreatic cancer; Hepatocellular carcinoma (HCC) therapy. |
Immunogen | n/a |
Other Names | ERBB3; erb-b2 receptor tyrosine kinase 3; HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3; receptor tyrosine-protein kinase erbB-3; proto-oncogene-like protein c-ErbB-3; human epidermal growth factor receptor 3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 |
Gene, Accession # | UniProt: P21860 |
Catalog # | FABIG-H333 |
Price | please inquire |
Order / More Info | HER3 + IGF1R (bispecific) Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |