Edit |   |
---|---|
Antigenic Specificity | Gβγ dimer |
Clone | monoclonal |
Host Species | Recombinant Camelid |
Reactive Species | bovine |
Isotype | n/a |
Format | single domain |
Size | n/a |
Concentration | n/a |
Applications | ELISA, WB, Inhib, |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Camelid Anti-Gβγ dimer Recombinant Single Domain Antibody (Nb5). This product is a recombinant Llama single domain antibody that recognizes Bovine Gβγ dimer. Nb5 binds and inhibits Gβ subtypes 1-4, showing its broad applicability to various cell types. Nb5 acts as a control-switch of GPCR-mediated cellular signaling by modulating PI3K-protein kinase B/AKT and MAPK-extracellular signal-regulated kinase (ERK) pathways. Nb5 does not alter Gαi-GTP-governed cellular levels of secondary messenger cyclic adenosine monophosphate (cAMP). Nb5 shows no effect on either Gαq-induced intracellular Ca2+ elevation or Gαs-induced cAMP production. |
Immunogen | n/a |
Other Names | G protein beta gamma dimer |
Gene, Accession # | n/a |
Catalog # | NBD-0042-YJ-VHH |
Price | please inquire |
Order / More Info | Gβγ dimer Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |