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Antigenic Specificity | C3b |
Clone | monoclonal |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | FuncS, Inhib, IP, ELISA, |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Human Anti-C3b Recombinant Antibody (clone S77). Recombinant Human Antibody (S77) is capable of binding to C3b, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-C3b mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-C3b proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody blocks binding of factor B to C3b inhibiting the first step in the formation of the alternative pathway C3 convertase. |
Immunogen | Human complement component 3 |
Other Names | C3; complement component 3; ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p; complement C3; prepro-C3; C3a anaphylatoxin; complement component C3; complement component C3a; complement component C3b; acylation-stimulating protein cleavage product; epididymis secretory sperm binding protein Li 62p; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; |
Gene, Accession # | UniProt: P01024 |
Catalog # | PABL-420 |
Price | please inquire |
Order / More Info | C3b Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |