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Antigenic Specificity | PDGFR2 + VEGFR2 Tandem Fab-ABR (bispecific immunotoxin) |
Clone | monoclonal |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | n/a |
Format | bispecific immunotoxin |
Size | n/a |
Concentration | n/a |
Applications | FuncS; Promising therapeutic agent; |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Anti-PDGFR2 x Anti-VEGFR2 Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin). Recombinant Anti-PDGFR2 x Anti-VEGFR2 Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) is designed to be expressed as the abrin-a A chain (ABRa-A) fused to a tandem Fab recognizing PDGFR2 and VEGFR2. It contains three chains and a His-tag at the C/N terminus for affinity purification. The two Fd regions are connected by a flexible linker. This bispecific immunotoxin can deliver ABRa-A to antigen-specific cells. Then ABR is a type II ribosome inactivating protein (RIP) and can kill the target cells. The bispecific immunotoxin is designed for the research of Cancers therapy. |
Immunogen | n/a |
Other Names | PDGFRA; PDGFR2; platelet derived growth factor receptor, alpha polypeptide; CD140a; Pdgfr-2; AI115593; platelet-derived growth factor receptor alpha; PDGFR-alpha; PDGF-R-alpha; PDGF alpha chain; CD140 antigen-like family member A; platelet-derived growth factor alpha receptor; alpha-type platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha) |
Gene, Accession # | UniProt: P16234 |
Catalog # | BSFAB-ABR017 |
Price | please inquire |
Order / More Info | PDGFR2 + VEGFR2 Tandem Fab-ABR (bispecific immunotoxin) Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |