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Antigenic Specificity | CTLA4 + PD1 Tandem Fab-PE (bispecific immunotoxin) |
Clone | monoclonal |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | n/a |
Format | bispecific immunotoxin |
Size | n/a |
Concentration | n/a |
Applications | FuncS; Promising therapeutic agent; |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-PE immunotoxin (Bispecific Immunotoxin). Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) is designed to be expressed as the Pseudomonas exotoxin (PE) fused to a tandem Fab recognizing CTLA4 and PD1. It contains three chains and a His-tag at the C/N terminus for affinity purification. The two Fd regions are connected by a flexible linker. This bispecific immunotoxin can deliver PE to antigen-specific cells. Then PE can inhibit protein synthesis and kill the target cells. The bispecific immunotoxin is designed for the research of autoimmune disease therapy. |
Immunogen | n/a |
Other Names | CTLA4; cytotoxic T-lymphocyte-associated protein 4; CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3; cytotoxic T-lymphocyte protein 4; CD152 isoform; celiac disease 3; insulin-dependent diabetes mellitus 12; cytotoxic T-lymphocyte-associated serine esterase-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4 |
Gene, Accession # | UniProt: P16410 |
Catalog # | BSFAB-PE025 |
Price | please inquire |
Order / More Info | CTLA4 + PD1 Tandem Fab-PE (bispecific immunotoxin) Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |