HER1 + HER3 Tandem Fab-RTA (bispecific immunotoxin) Antibody from CREATIVE BIOLABS, INC.

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Antigenic SpecificityHER1 + HER3 Tandem Fab-RTA (bispecific immunotoxin)
Clonemonoclonal
Host SpeciesRecombinant Human
Reactive Specieshuman
Isotypen/a
Formatbispecific immunotoxin
Sizen/a
Concentrationn/a
ApplicationsFuncS; Promising therapeutic agent;
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DescriptionRecombinant Human Anti-HER1 x Human Anti-HER3 Tandem Fab-RTA immunotoxin (Bispecific Immunotoxin). Recombinant Anti-HER1 x Anti-HER3 Tandem Fab-RTA immunotoxin (Bispecific Immunotoxin) is designed to be expressed as the Ricin A chain (RTA) fused to a tandem Fab recognizing HER1 and HER3. It contains three chains and a His-tag at the C/N terminus for affinity purification. The two Fd regions are connected by a flexible linker. This bispecific immunotoxin can deliver RTA to antigen-specific cells. Then RTA can damage ribosomes, inhibit protein synthesis and kill the target cells. The bispecific immunotoxin is designed for the research of Head and neck cancer; Colorectal cancer therapy.
Immunogenn/a
Other NamesEGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
Gene, Accession #UniProt: P00533
Catalog #BSFAB-RTA031
Priceplease inquire
Order / More InfoHER1 + HER3 Tandem Fab-RTA (bispecific immunotoxin) Antibody from CREATIVE BIOLABS, INC.
Product Specific Referencesn/a
CREATIVE BIOLABS, INC.
CREATIVE BIOLABS, INC.
CREATIVE BIOLABS, INC.
Suite 203
17 Ramsey Road
Shirley NY 11967
P: 1-631-416-1478
F: 1-631-207-8356

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