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Antigenic Specificity | CEA + GD2 Tandem Fab-MEL (bispecific immunotoxin) |
Clone | monoclonal |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | n/a |
Format | bispecific immunotoxin |
Size | n/a |
Concentration | n/a |
Applications | FuncS; Promising therapeutic agent; |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Human Anti-CEA x Human Anti-GD2 Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin). Recombinant Anti-CEA x Anti-GD2 Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin) is designed to be expressed as the Melittin (MEL) fused to a tandem Fab recognizing CEA and GD2. It contains three chains and a His-tag at the C/N terminus for affinity purification. The two Fd regions are connected by a flexible linker. This bispecific immunotoxin can deliver MEL to antigen-specific cells. Then MEL is a cytolytic peptide and can kill the target cells. The bispecific immunotoxin is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors therapy. |
Immunogen | n/a |
Other Names | CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100 |
Gene, Accession # | UniProt: A0A024R0K5 |
Catalog # | BSFAB-MEL023 |
Price | please inquire |
Order / More Info | CEA + GD2 Tandem Fab-MEL (bispecific immunotoxin) Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |