BCMA (immunotoxin) Antibody from CREATIVE BIOLABS, INC.
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| Antigenic Specificity | BCMA (immunotoxin) |
| Clone | monoclonal |
| Host Species | Human |
| Reactive Species | human |
| Isotype | n/a |
| Format | Pseudomonas exotoxin conjugate |
| Size | n/a |
| Concentration | n/a |
| Applications | Cytotoxicity assay, Functional assay, |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | BAFF-PE immunotoxin. This immunotoxin was achieved by conjugating/fusing the BAFF to Pseudomonas exotoxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to BCMA expressing B cells and enters cells by receptor-mediated endocytosis, then PE cleaved fragments the size of Mr 37000 and 27000, the large fragment and finally into the Golgi and elongation factor 2 (EM) combining it glycosylation inactivation, inhibition of protein synthesis, leading to apoptosis. It was designed for treatment of B cell leukemias. |
| Immunogen | n/a |
| Other Names | B cell maturation antigen; B cell maturation factor; B cell maturation protein; B-cell maturation protein; BCM; BCMA; CD269; CD269 antigen; TNFRSF17; TNR17_HUMAN; Tumor necrosis factor receptor superfamily member 17; B cell leukemias; Pseudomonas exotoxin; Pseudomonas exotoxin A; Pseudomonas aeruginosa exotoxin; Pseudomonas aeruginosa exotoxin A; PE; PE38; PE40; ETA; PE33; PE35 |
| Gene, Accession # | UniProt: Q02223 |
| Catalog # | AGTO-L075E |
| Price | please inquire |
| Order / More Info | BCMA (immunotoxin) Antibody from CREATIVE BIOLABS, INC. |
| Product Specific References | n/a |
CREATIVE BIOLABS, INC.
CREATIVE BIOLABS, INC.
Suite 203
17 Ramsey Road
Shirley NY 11967
P: 1-631-416-1478
F: 1-631-207-8356
info@creative-biolabs.com
http://www.creative-biolabs.com
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