GAD65 GAD67 Antibody from CREATIVE BIOLABS, INC.
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| Edit | |
|---|---|
| Antigenic Specificity | GAD65 GAD67 |
| Clone | CBP984 |
| Host Species | Rabbit |
| Reactive Species | mouse; rat; human; |
| Isotype | n/a |
| Format | unconjugated |
| Size | n/a |
| Concentration | n/a |
| Applications | IP; IHC-P; IHC-Fr; WB; ICC; IF; |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | NeuroMab™ Rabbit Anti-GAD65/GAD67 Monoclonal Antibody (CBP984) |
| Immunogen | Recombinant fragment Within Mouse GAD65 + GAD67 aa 450 to the C-terminus. The exact sequence is proprietary. Database link: P48318 |
| Other Names | Glutamate decarboxylase or glutamate decarboxylase (GAD) is an enzyme that catalyzes the decarboxylation of glutamate into GABA and CO 2. GAD uses PLP as a cofactor. The reaction proceeds as follows: HOOC-CH2-CH2-CH(NH2)-COOH→CO2 + HOOC-CH2-CH2-CH2NH2 In mammals; GAD exists in two isoforms with molecular weights of 67 and 65 kDa (GAD67 and GAD65); which are encoded by two different genes on different chromosomes (GAD1 and GAD2 genes; which are human 2 and Chromosome 10). GAD67 and GAD65 are expressed in the brain using GABA as a neurotransmitter; and are also expressed in insulin-producing beta cells of the pancreas; depending on the species. These two enzymes together maintain the main physiological supply of mammalian GABA; although it may also be caused by the enteric nervous system; brain; and other places through the action of diamines Synthesized from putrescine. Oxidase and aldehyde dehydrogenase 1a1. Several truncated transcripts and peptides of GAD67 can be detected in the developing brain; but their function (if any) is unknown. |
| Gene, Accession # | UniProt: Q05329(GAD2) |
| Catalog # | NAB-0720-Z3848 |
| Price | please inquire |
| Order / More Info | GAD65 GAD67 Antibody from CREATIVE BIOLABS, INC. |
| Product Specific References | n/a |
CREATIVE BIOLABS, INC.
CREATIVE BIOLABS, INC.
Suite 203
17 Ramsey Road
Shirley NY 11967
P: 1-631-416-1478
F: 1-631-207-8356
info@creative-biolabs.com
http://www.creative-biolabs.com
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