SCLC1 + CD3 (bispecific) Antibody from CREATIVE BIOLABS, INC.
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| Antigenic Specificity | SCLC1 + CD3 (bispecific) |
| Clone | monoclonal |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | n/a |
| Format | bispecific |
| Size | n/a |
| Concentration | n/a |
| Applications | FuncS; Promising therapeutic agent; |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recombinant Human Anti-SCLC1 x Human Anti-CD3 Bispecific Antibody (Single-chain Triplebody). Recombinant Anti-SCLC1 x Anti-CD3 Bispecific Antibody (Single-chain Triplebody) is designed to be expressed as a single chain with three scFv units, two distal binding sites for SCLC1 and a central site for CD3. It contains a His-tag at the C/N terminus for affinity purification. This BsAb can retarget T cells to tumor cells. It is designed for the research of Small cell lung cancer therapy. |
| Immunogen | n/a |
| Other Names | CD3 (Cluster of differentiation 3), originally known as T3, is one of the first groups of human T lymphocyte surface antigens recognized by monoclonal antibodies. It has been reported that antibodies against CD3 could either stimulate T cells to divide or inhibit the progress of effector functions according to the conditions used. It plays an important role in T cell and the CD3 T-cell co-receptor helps to activate the cytotoxic T-Cell and T helper cells. The CD3 molecule is composed of a protein complex and consists of four distinct chains. The complex of mammals contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. All these chains associate with T-cell receptor and the ζ-chain to generate an activation signal in T lymphocytes. |
| Gene, Accession # | UniProt: P07766 |
| Catalog # | SCTB-H172 |
| Price | please inquire |
| Order / More Info | SCLC1 + CD3 (bispecific) Antibody from CREATIVE BIOLABS, INC. |
| Product Specific References | n/a |
CREATIVE BIOLABS, INC.
CREATIVE BIOLABS, INC.
Suite 203
17 Ramsey Road
Shirley NY 11967
P: 1-631-416-1478
F: 1-631-207-8356
info@creative-biolabs.com
http://www.creative-biolabs.com
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