IL-15R (immunotoxin) Antibody from CREATIVE BIOLABS, INC.
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| Antigenic Specificity | IL-15R (immunotoxin) |
| Clone | monoclonal |
| Host Species | Rat |
| Reactive Species | human |
| Isotype | n/a |
| Format | Pseudomonas exotoxin conjugate |
| Size | n/a |
| Concentration | n/a |
| Applications | Cytotoxicity assay, Function study, |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IL-15-PE immunotoxin. This immunotoxin was achieved by conjugating/fusing the IL-15 to Pseudomonas exotoxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to interleukin-15 receptor (IL-15R)-overexpressing cells. Once bind, the toxin enters cells by receptor-mediated endocytosis. Then PE cleaved fragments the size of Mr 37000 and 27000, the large fragment and finally into the Golgi and elongation factor 2 (EM) combining it glycosylation inactivation, inhibition of protein synthesis, leading to apoptosis. It was designed for treating arthritis. |
| Immunogen | n/a |
| Other Names | IL15RA; interleukin 15 receptor, alpha; CD215; interleukin-15 receptor subunit alpha; interleukin 15 receptor alpha isoform EM2; interleukin 15 receptor alpha isoform IC2; interleukin 15 receptor alpha isoform IC3; interleukin 15 receptor alpha isoform IC4; interleukin 15 receptor alpha isoform IC5; interleukin 15 receptor alpha isoform IC6; interleukin 15 receptor alpha isoform IC7; interleukin 15 receptor alpha isoform IC8; Pseudomonas exotoxin; Pseudomonas exotoxin A; Pseudomonas aeruginosa exotoxin; Pseudomonas aeruginosa exotoxin A; PE; PE38; PE40; ETA; PE33; PE67 |
| Gene, Accession # | UniProt: Q13261 |
| Catalog # | AGTO-G041E |
| Price | please inquire |
| Order / More Info | IL-15R (immunotoxin) Antibody from CREATIVE BIOLABS, INC. |
| Product Specific References | n/a |
CREATIVE BIOLABS, INC.
CREATIVE BIOLABS, INC.
Suite 203
17 Ramsey Road
Shirley NY 11967
P: 1-631-416-1478
F: 1-631-207-8356
info@creative-biolabs.com
http://www.creative-biolabs.com
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