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Antigenic Specificity | HLA-A2 |
Clone | monoclonal |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | ELISA, FC, IHC, Cyt, |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse Anti-HLA-A2 Recombinant Antibody (clone G1). A recombinant Ab that exhibits a characteristic TCR-like binding specificity, yet, unlike TCRs, it did so with a high affinity in the nanomolar range. The TCR-like Ab can recognize the native MHC-peptide complex expressed on the surface of APCs, and on peptide-pulsed or native melanoma cells. Moreover, when fused to a very potent cytotoxic effector molecule in the form of a truncated bacterial toxin, it was able to specifically kill APCs in a peptide-dependent manner. |
Immunogen | A single-chain HLA-A2, complexed with a common antigenic T cell HLA-A2-restricted epitope derived from the melanoma differentiation Ag gp100. |
Other Names | HLA-A; Major histocompatibility complex, class I, A; HLAA |
Gene, Accession # | n/a |
Catalog # | FAMAB-0167YC |
Price | please inquire |
Order / More Info | HLA-A2 Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |