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Antigenic Specificity | Cd8b1 |
Clone | monoclonal |
Host Species | Recombinant Rat |
Reactive Species | mouse |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | Neut, |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat Anti-Cd8b1 Recombinant Antibody (clone YTS156.7.7). The YTS156.7 mAb inhibits this interaction and blocks T cell activation. To elucidate the molecular basis for this inhibition, the crystal structure of the CD8alphabeta immunoglobulin-like ectodomains were determined in complex with mAb YTS156.7 Fab at 2.7 A resolution. The YTS156.7 epitope on CD8beta was identified and implies that residues in the CDR1 and CDR2-equivalent loops of CD8beta are occluded upon binding to class I pMHC. |
Immunogen | n/a |
Other Names | Cd8b; Ly-3; Ly-C; Lyt-3 |
Gene, Accession # | UniProt: P10300 |
Catalog # | HPAB-S0182-YC |
Price | please inquire |
Order / More Info | Cd8b1 Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |