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Antigenic Specificity | HCMV gB |
Clone | monoclonal |
Host Species | Recombinant Human |
Reactive Species | HCMV |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | Neut, |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Human Anti-HCMV gB Antibody (SM5-1). Recombinant Human Antibody (SM5-1) is capable of binding to HCMV gB, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-HCMV gB mAb and CH1-3 region of human IgG and a light chain (LC) encoding VL from anti-HCMV gB proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. SM5-1 neutralizes HCMV either by blocking the pre- to postfusion transition of gB or by precluding the interaction with additional effectors such as the gH/gL complex. |
Immunogen | n/a |
Other Names | gB; UL55; Envelope glycoprotein B; type 1 membrane protein; possible membrane fusogen; binds cell surface heparan sulphate; involved in cell entry |
Gene, Accession # | UniProt: P13201 |
Catalog # | PABC-231 |
Price | please inquire |
Order / More Info | HCMV gB Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |