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Antigenic Specificity | HER1 + HER3 (bispecific) |
Clone | monoclonal |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | n/a |
Format | bispecific |
Size | n/a |
Concentration | n/a |
Applications | FuncS; Promising therapeutic agent; |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (Minibody). Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Minibody) is designed to be expressed as the anti-HER1 scFv fused to N-terminus of Knob-CH3 domain and the anti-HER3 scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can bind and inactivate two receptors simultaneously. It is designed for the research of Head and neck cancer; Colorectal cancer therapy. |
Immunogen | n/a |
Other Names | EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog |
Gene, Accession # | UniProt: P00533 |
Catalog # | MiniB-H330 |
Price | please inquire |
Order / More Info | HER1 + HER3 (bispecific) Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |