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Antigenic Specificity | DNMT1 + SHH (bispecific) |
Clone | monoclonal |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | n/a |
Format | bispecific |
Size | n/a |
Concentration | n/a |
Applications | FuncS; Promising therapeutic agent; |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Anti-DNMT1 x Anti-SHH Bispecific Antibody (Triple Body). Recombinant Anti-DNMT1 x Anti-SHH Bispecific Antibody (Triple Body) is designed to be expressed as two polypeptide chains respectively. The Fd fragment and LC from an anti-DNMT1 antibody are both extended with the scFv fragment from an anti-SHH antibody. This BsAb can bind two factors simultaneously, block Hedgehog binding to PTCH, downregulate of DNMT1 and block DNA methylation. It is designed for the research of Hormone refractory breast cancer (HRBC) therapy. |
Immunogen | n/a |
Other Names | AIM; DNMT; MCMT; CXXC9; HSN1E; ADCADN; DNA methyltransferase 1; DNMT1 |
Gene, Accession # | UniProt: I6L9H2 |
Catalog # | TRIB-150 |
Price | please inquire |
Order / More Info | DNMT1 + SHH (bispecific) Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |