HER3 + IGF1R Tandem Fab-BGN (bispecific immunotoxin) Antibody from CREATIVE BIOLABS, INC.
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| Antigenic Specificity | HER3 + IGF1R Tandem Fab-BGN (bispecific immunotoxin) |
| Clone | monoclonal |
| Host Species | Recombinant Mouse |
| Reactive Species | human |
| Isotype | n/a |
| Format | bispecific immunotoxin |
| Size | n/a |
| Concentration | n/a |
| Applications | FuncS; Promising therapeutic agent; |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recombinant Anti-HER3 x Anti-IGF1R Tandem Fab-BGN immunotoxin (Bispecific Immunotoxin). Recombinant Anti-HER3 x Anti-IGF1R Tandem Fab-BGN immunotoxin (Bispecific Immunotoxin) is designed to be expressed as the Bouganin (BGN) fused to a tandem Fab recognizing HER3 and IGF1R. It contains three chains and a His-tag at the C/N terminus for affinity purification. The two Fd regions are connected by a flexible linker. This bispecific immunotoxin can deliver BGN to antigen-specific cells. Then BGN is a single chain, type I ribosone inactivating protein (RIP) and can kill the target cells. The bispecific immunotoxin is designed for the research of Pancreatic cancer; Hepatocellular carcinoma (HCC) therapy. |
| Immunogen | n/a |
| Other Names | ERBB3; erb-b2 receptor tyrosine kinase 3; HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3; receptor tyrosine-protein kinase erbB-3; proto-oncogene-like protein c-ErbB-3; human epidermal growth factor receptor 3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 |
| Gene, Accession # | UniProt: P21860 |
| Catalog # | BSFAB-BGN016 |
| Price | please inquire |
| Order / More Info | HER3 + IGF1R Tandem Fab-BGN (bispecific immunotoxin) Antibody from CREATIVE BIOLABS, INC. |
| Product Specific References | n/a |
CREATIVE BIOLABS, INC.
CREATIVE BIOLABS, INC.
Suite 203
17 Ramsey Road
Shirley NY 11967
P: 1-631-416-1478
F: 1-631-207-8356
info@creative-biolabs.com
http://www.creative-biolabs.com
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