Edit |   |
---|---|
Antigenic Specificity | SNCA |
Clone | monoclonal |
Host Species | Recombinant human |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | FC, IF, FuncS, |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Anti-human SNCA Intrabody [(D-Arg)9]. Recombinant anti-SNCA intrabody linked to (D-Arg)9 works within cells to bind human monomeric wild-type SNCA, expressed in E. coli cells. The intrabody stabilizes detergent-soluble monomeric syn and inhibits the formation of detergent-insoluble high-molecular-weight syn species. In addition, the intrabody ameliorates the decreased cell adhesion that characterizes the syn-overexpressing cells. Anti-SNCA intrabodies may represent novel molecular therapeutics for synucleinopathies, with implications for other neurodegenerative disorders caused by misfolded accumulated proteins. |
Immunogen | human synuclein, alpha (non A4 component of amyloid precursor) |
Other Names | SNCA; synuclein, alpha (non A4 component of amyloid precursor); PD1; NACP; PARK1; PARK4; alpha-synuclein; synuclein alpha-140; non A-beta component of AD amyloid |
Gene, Accession # | UniProt: P37840 |
Catalog # | IAB-B031(A) |
Price | please inquire |
Order / More Info | SNCA Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |