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Antigenic Specificity | CD20 |
Clone | monoclonal |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | FC, IP, ELISA, Neut, FuncS, IF, IHC, |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Human CD20 Recombinant Antibody (Ofatumumab). Recombinant monoclonal antibody to Human CD20. Ofatumumab (trade name Arzerra, also known as HuMax-CD20) is a human monoclonal antibody (for the CD20 protein) which appears to inhibit early-stage B lymphocyte activation. It is FDA approved for treating chronic lymphocytic leukemia that is refractory to fludarabine and Campath and has also shown potential in treating Follicular non-Hodgkin's lymphoma, Diffuse large B cell lymphoma, rheumatoid arthritis and relapsing remitting multiple sclerosis. Ofatumumab has also received conditional approval in Europe for the treatment of refractory chronic lymphocytic leukemia. This makes ofatumumab the first marketing application for an antibody, as well as the first human monoclonal antibody which targets the CD20 molecule that will be available for patients with refractory CLL. |
Immunogen | Hmuan CD20 transfected NS/O cells. |
Other Names | Ofatumumab;arzerra;679818-59-8;GSK1841157;HuMax-CD20;2F2;Arzerra;HuMax-CD20;MS4A1;membrane-spanning 4-domains, subfamily A, member 1;CD20;B-lymphocyte antigen CD20;B1;Bp35;CD20 antigen;CD20 receptor;leukocyte surface antigen Leu-16;B-lymphocyte cell |
Gene, Accession # | UniProt: P11836 |
Catalog # | TAB-028 |
Price | please inquire |
Order / More Info | CD20 Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |