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Antigenic Specificity | FKBP5/FKBP51 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: orangutan) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-FKBP5/FKBP51 Antibody, Affinity Purified. FKBP5/FKBP51 is an immunophilin and target of FK506, a macrolide immunosuppressive drug derived from Streptomyces tsukubaensis. Like other FK506 binding proteins, FKBP5/FKBP51 exhibits peptidyl-prolyl cis-trans isomerase activity. The most studied role of FKBP5/FKBP51 surrounds its involvement in the regulation of steroid receptor signaling. In association with the molecular chaperones Hsp90 and Hsp70, FKBP5/FKBP51 is able to influence steroid-hormone binding affinity and transcriptional activity. Recently, FKBP5/FKBP51 has become of interest in the field of psychiatry due to its potential role in cortisol regulation and its relation to mood disorders. |
Immunogen | Epitope: between 225 and 275 |
Other Names | HSP90-binding immunophilin; peptidylprolyl cis-trans isomerase; PPIase; PPIase FKBP5; Ptg-10; T-cell FK506-binding protein; FKBP54; P54; rotamase; 54 kDa progesterone receptor-associated immunophilin; 51 kDa FK506-binding protein; peptidyl-prolyl cis-trans isomerase FKBP5; FKBP-51; 51 kDa FKBP; AIG6; androgen-regulated protein 6; FF1 antigen; FK506-binding protein 5; FKBP-5; FKBP51 |
Gene, Accession # | Gene ID: 2289, Accession: NP_004108.1, UniProt: Q13451 |
Catalog # | A301-429A-T |
Price | $121 |
Order / More Info | FKBP5/FKBP51 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |