Spt16 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | Spt16 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, (presumed: mouse) |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 1000 µg/ml |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-Spt16 Antibody, Affinity Purified. Spt16 is a Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is composed of two subunits: SSRP1 and Spt16. It is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, and then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y5B9]. |
| Immunogen | Epitope: between 997 and 1047 |
| Other Names | FACTP140; SPT16/CDC68; chromatin-specific transcription elongation factor 140 kDa subunit; SPT16; suppressor of Ty 16 homolog; hSPT16; FACT 140 kDa subunit; facilitates chromatin remodeling 140 kDa subunit; CDC68; facilitates chromatin transcription complex subunit SPT16; FACT complex subunit SPT16 |
| Gene, Accession # | Gene ID: 11198, Accession: NP_009123.1, UniProt: Q9Y5B9 |
| Catalog # | A302-492A-T |
| Price | $121 |
| Order / More Info | Spt16 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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