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Antigenic Specificity | PAM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: mouse) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 200 µg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-PAM Antibody, Affinity Purified. In addition to its possible functions as a facilitator of Myc activated transcription, PAM (protein associated with Myc) has also been shown to play a role in mTOR signaling. PAM functions as an E3 ubiquitin ligase for tuberin (TSC2), a negative regulator of the mTOR pathway. Additionally PAM has been shown to function as a guanosine exchange factor (GEF) for Rheb and to facilitate sphingosine-1-phosphate signaling in the mTOR pathway. |
Immunogen | Epitope: between 2425 and 2475 |
Other Names | pam/highwire/rpm-1 protein; E3 ubiquitin-protein ligase MYCBP2; RING-type E3 ubiquitin transferase MYCBP2; protein associated with Myc; Phr; PAM; Myc-bp2; Highwire; myc-binding protein 2 |
Gene, Accession # | Gene ID: 23077, Accession: NP_055872.3, UniProt: O75592 |
Catalog # | A301-833A |
Price | $433 |
Order / More Info | PAM Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |