IRS1 Antibody from FORTIS LIFE SCIENCES
Search, find, compare suppliers for anti-IRS1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | IRS1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, (presumed: mouse, rat) |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 1000 µg/ml |
| Applications | IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-IRS1 Antibody, Affinity Purified. The insulin receptor substrate 1 (IRS1) is one of four members of the IRS family (IRS1-4) that mediates intracellular signaling downstream of the IGF1 and insulin receptors. Phosphorylation of IRS1 by activated receptors leads to binding of IRS to the SH2 domains of effector proteins such as PI3K, Grb2, nck, and SHP2. The downstream effects of insulin and IGF1 signaling via IRSs on the cell are pleiotropic and include various responses such as glucose transport, glycogen synthesis, protein synthesis, antilipolysis, and gluconeogenesis. Polymorphisms in IRS1 may contribute to the etiology of non-insulin-dependent diabetes mellitus (NIDDM). |
| Immunogen | Epitope: between 750 and 800 |
| Other Names | HIRS-1; insulin receptor substrate 1; IRS-1 |
| Gene, Accession # | Gene ID: 3667, Accession: NP_005535.1, UniProt: P35568 |
| Catalog # | A301-157A-T |
| Price | $121 |
| Order / More Info | IRS1 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
1440 Main Street, Suite 300
Waltham MA 02451
P: 800.338.9579
info@fortislife.com
https://www.fortislife.com
Profile of FORTIS LIFE SCIENCES
Return to Antibodies