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Antigenic Specificity | DUSP12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-DUSP12 Antibody, Affinity Purified. Dual specificity protein phosphatase 12 (DUSP12) is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP12 is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain [taken from NCBI Entrez Gene (Gene ID: 11266)]. |
Immunogen | Epitope: between 1 and 50 |
Other Names | serine/threonine specific protein phosphatase; YVH1; YVH1 protein-tyrosine phosphatase ortholog; dual specificity protein phosphatase 12; dual specificity tyrosine phosphatase YVH1; DUSP1 |
Gene, Accession # | Gene ID: 11266, Accession: NP_009171.1, UniProt: Q9UNI6 |
Catalog # | A305-588A-T |
Price | $121 |
Order / More Info | DUSP12 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |