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Antigenic Specificity | CDC25c |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, (presumed: orangutan, gorilla, chimpanzee) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 250 µg/ml |
Applications | IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-CDC25c IHC Antibody, Affinity Purified. CDC25c (cell division cycle 25 homolog c) is a member of the Cdc25 family of phosphatases. CDC25c promotes cell cycle progression and M-phase entry by dephosphorylating CDC2/cyclin B and activating its kinase activity. CDC25c is phosphorylated and activated by multiple kinases including chk1, Cdc2/cyclin B, polo-like kinase 1, and JNK MAP kinases. The inactivation of CDC25c phosphatase activity is achieved through dephosphorylation by PP1 and PP2A phosphatases. |
Immunogen | Epitope: between 150 and 200 |
Other Names | dual specificity phosphatase CDC25C; protein phosphatase 1, regulatory subunit 60; PPP1R60; phosphotyrosine phosphatase; mitosis inducer CDC25; CDC25; M-phase inducer phosphatase 3 |
Gene, Accession # | Gene ID: 995, Accession: NP_001781.2, UniProt: P30307 |
Catalog # | IHC-00286 |
Price | $459 |
Order / More Info | CDC25c Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |