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Antigenic Specificity | Insulin Receptor Beta |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Insulin Receptor Beta Antibody, Affinity Purified. The insulin receptor is a receptor tyrosine kinase that mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates to stimulate uptake of glucose. The insulin receptor is synthesized as a single polypeptide that is cleaved to generate an alpha and beta subunit. The subunit structure of the insulin receptor consists of a tetramer of two alpha and two beta chains linked by disulfide bonds. |
Immunogen | Epitope: between 1332 and 1382 |
Other Names | IR; CD antigen CD220; CD220; HHF5; insulin receptor |
Gene, Accession # | Gene ID: 3643, Accession: NP_000199.2, UniProt: P06213 |
Catalog # | A303-712A |
Price | $433 |
Order / More Info | Insulin Receptor Beta Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |