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Antigenic Specificity | Presenilin-2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: mouse, rat, bovine, porcine, orangutan) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Presenilin-2 Antibody, Affinity Purified. Presenilin-2 is a probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Presenilin-2 requires the other members of the gamma-secretase complex to have a protease activity. It may play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. It may function in the cytoplasmic partitioning of proteins [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P49810]. |
Immunogen | Epitope: between 275 and 325 |
Other Names | AD5; STM2; PS-2; PS2; STM-2; presenilin-2; Alzheimer disease 4; AD4; AD3LP; AD3L; E5-1; CMD1V |
Gene, Accession # | Gene ID: 5664, Accession: NP_000438.2, UniProt: P49810 |
Catalog # | A304-342A-T |
Price | $121 |
Order / More Info | Presenilin-2 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |