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Antigenic Specificity | NPAT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: mouse) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-NPAT Antibody, Affinity Purified. NPAT (nuclear protein of the ataxia telangiectasia mutated locus) is required for progression through the G1 and S phases of the cell cycle and for S phase entry. It activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. NPAT also positively regulates the ATM, MIZF and PRKDC promoters. Transcriptional activation may be accomplished at least in part by the recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/Q14207]. |
Immunogen | Epitope: between 1377 and 1427 |
Other Names | nuclear protein of the ataxia telangiectasia mutated locus; p220; nuclear protein, co-activator of histone transcription; nuclear protein of the ATM locus; E14/NPAT; E14; protein NPAT; nuclear protein, ataxia-telangiectasia locus |
Gene, Accession # | Gene ID: 4863, Accession: NP_002510.2, UniProt: Q14207 |
Catalog # | A302-772A-T |
Price | $121 |
Order / More Info | NPAT Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |