VRK1 Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificityVRK1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size10 µl
Concentration1000 µg/ml
ApplicationsIP
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DescriptionRabbit anti-VRK1 Antibody, Affinity Purified. Vaccinia-related kinase 1 is a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases.VRK1 is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This protein, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN [taken from NCBI Entrez Gene (Gene ID: 7443)].
ImmunogenEpitope: between 1 and 50
Other NamesPCH1A; vaccinia virus B1R-related kinase 1; Vaccinia-related kinase 1; PCH1; serine/threonine-protein kinase VRK1; vaccinia related kinase 1
Gene, Accession #Gene ID: 7443, Accession: NP_003375.1, UniProt: Q99986
Catalog #A305-268A-T
Price$121
Order / More InfoVRK1 Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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