ApoA1 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | ApoA1 |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | human |
| Isotype | n/a |
| Format | biotin conjugate |
| Size | 1 mg |
| Concentration | 1 mg/ml |
| Applications | n/a |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Goat anti-Human Apo AI [B03] Antibody, Affinity Purified. Apo A1 comprises approximately 70% of the protein moiety in HDL. It is a single polypeptide chain consisting of 243 amino acid residues without disulfide bound and with glutamic acid as the C-terminal residue and aspartic acid as the N-terminal residue. The molecular weight is reported to be 28 kDa (Brewer et al., 1978). The roles of Apo A1 in HDL function include reverse cholesterol transportation, lipid cholesterol binding, lecithin-cholesterol acyl transferase (LCAT) activation, and receptor binding, which is responsible for cholesterol esterification in plasma. Besides participate in cholesterol metabolism, Apo A1 and HDL also suppress neutrophil activation, inhibit bacterial endotoxin, induce trypanosomal lysis, and other physiological activities. (Brouillette et al., 2001). Apo A1 levels may be inversely related to the risk of coronary disease. In previous research, Apo A1 may affect diet-induced inflammation by either directly or indirectly altering lipid rafts. (Cheng et al., 2012) |
| Immunogen | Human Apolipoprotein AI |
| Other Names | epididymis secretory sperm binding protein; apo-AI; ApoA-I; Apolipoprotein A1; apolipoprotein A-I; apo(a) |
| Gene, Accession # | Gene ID: 335, Accession: NP_000030.1, UniProt: P02647 |
| Catalog # | A81-104B |
| Price | $339 |
| Order / More Info | ApoA1 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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