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Antigenic Specificity | ROCK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: mouse, rat, bovine) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-ROCK2 Antibody, Affinity Purified. Rho-associated protein kinase 2 (ROCK2), or Rho kinase alpha, is a serine-threonine protein kinase that plays an important role in cellular apoptosis, growth, cell motility and cell contraction. ROCK2 shares an overall 65% homology in amino acid sequence with ROCK1. The ROCK1 and ROCK2 isoforms are products of two separate genes. Both ROCK1 and ROCK2 are downstream targets of the Rho A small GTP-binding protein. As downstream effectors of RhoA, ROCK1 and ROCK2 mediate changes in the actin cytoskeleton via phosphorylation of target proteins such as the MBS subunit of MLCP, MLC, ERM proteins, protein LIM kinase and adducin. |
Immunogen | Epitope: between 1320 and C-term |
Other Names | rho-associated protein kinase 2; ROCK-II; Rho-associated, coiled-coil-containing protein kinase 2; Rho kinase 2; p164 ROCK-2; rho-associated, coiled-coil-containing protein kinase II |
Gene, Accession # | Gene ID: 9475, Accession: NP_004841.1, UniProt: O75116 |
Catalog # | A300-047A |
Price | $433 |
Order / More Info | ROCK2 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |