vPARP Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificityvPARP
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size10 µl
Concentration1000 µg/ml
ApplicationsIP
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DescriptionRabbit anti-vPARP Antibody, Affinity Purified. PARP4 [poly(ADP-ribose) polymerase family, member 4] catalyzes the formation of ADP-ribose polymers covalently attached to proteins using NAD+ as a substrate. There are 6 mammalian PARP enzymes: PARP1, PARP2, PARP3, PARP4/vPARP, PARP5/Tankyrase-1, and PARP6/Tankyrase-2. PARP4 is also known as vault PARP (vPARP) due to its association with the vault particle, a 13MDa cytoplasmic ribonucleoprotein complex whose barrel-shaped structure resembles arched cathedral ceilings. vPARP has also been identified separate from the vault particle. It has been localized to the nuclear pore, mitotic spindle, and cytoplasm. It also has been shown to associate with telomerase activity. Studies of vPARP knockout mice show an increased susceptibility to carcinogen-induced tumorigenesis.
ImmunogenEpitope: between 1400 and 1450
Other NamesVPARP; PH5P; poly [ADP-ribose] polymerase 4; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase-like 1; vault poly(ADP-ribose) polymerase; vault protein, 193-kDa; von Willebrand factor A domain containing 5C; PARP-4; VWA5C; VAULT3; ADP-ribosyltransferase diphtheria toxin-like 4; PARP-related; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 1; PARP-related/IalphaI-related H5/proline-rich; ADPRTL1; ARTD4; H5 proline-rich; I-alpha-I-related; p193; PARPL; 193 kDa vault protein
Gene, Accession #Gene ID: 143, Accession: NP_006428.2, UniProt: Q9UKK3
Catalog #A301-953A-T
Price$121
Order / More InfovPARP Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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