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Antigenic Specificity | RLIP76 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-RLIP76 Antibody, Affinity Purified. 76 kDa Ral-interacting protein (RLIP76) can activate, specifically, hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. RLIP76 mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. It can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. It serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15311]. |
Immunogen | Epitope: between 600 and 650 |
Other Names | RalBP1; RLIP76; RLIP1; ral-interacting protein 1; ralA-binding protein 1; DNP-SG ATPase; dinitrophenyl S-glutathione ATPase; 76 kDa Ral-interacting protein; RIP1 |
Gene, Accession # | Gene ID: 10928, Accession: NP_006779.1, UniProt: Q15311 |
Catalog # | A304-497A |
Price | $433 |
Order / More Info | RLIP76 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |