MAML2 Antibody from FORTIS LIFE SCIENCES
Search, find, compare suppliers for anti-MAML2 antibody, protein, ELISA kits.
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| Antigenic Specificity | MAML2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, (presumed: bovine) |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 200 µg/ml |
| Applications | WB, IP, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-MAML2 Antibody, Affinity Purified. There are 3 MAML (mastermind-like) proteins in mammals (MAML1-3). MAML2 is a critical coactivator for NOTCH signaling. MAML2 associates with NOTCH and CSL in a ternary complex and functions to activate transcription of HES and hairy-related basic helix-loop-helix transcription factors. MAML2 has been identified in a chromosomal rearrangement and fusion with MECT1 in mucoepidermoid carcinomas, secondary acute myeloid leukemia, hidradenomas, and myelodysplastic syndrome. MECT1 is a CREB regulator, and when fused with the transactivational domain of MAML2, imparts constitutive activation of CREB-dependent transcription that may promote oncogenesis. |
| Immunogen | Epitope: between 1100 and C-term |
| Other Names | mastermind-like 2; mastermind-like protein 2; MAM-3; MAM3; mam-2; MAM2; MLL-MAML2 |
| Gene, Accession # | Gene ID: 84441, Accession: AAK93831.1, UniProt: Q8IZL2 |
| Catalog # | A300-682A-T |
| Price | $121 |
| Order / More Info | MAML2 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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