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Antigenic Specificity | SETDB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-SETDB1 Antibody, Affinity Purified. SETDB1 (SET domain, bifurcated 1) is a member of the SET (SuVar3-9, enhancer of Zeste, Trithorax) domain-containing protein family that functions as a histone and DNA methyltransferase. SETDB1 was identified through its interaction with ERG (ets-related gene) and KAP1 (KRAB-associated protein1) and was later demonstrated to interact with HDAC1/2 (histone deacetylase 1/2), DNA methyltransferase 3s (DNMT3s), mSin3A/3B, HP1, and MBD1. SETDB1 is suggested to play a role in transcriptional repression important to early development. |
Immunogen | Epitope: between 1125 and 1175 |
Other Names | histone-lysine N-methyltransferase SETDB1; TDRD21; SET domain bifurcated 1; lysine N-methyltransferase 1E; KMT1E; tudor domain containing 21; histone-lysine N-methyltransferase, H3lysine-9 specific 4; H3-K9-HMTase4; H3-K9-HMTase 4; ESET; ERG-associated protein with SET domain; ERG-associated protein with a SET domain, ESET; KG1T; histone H3-K9 methyltransferase 4 |
Gene, Accession # | Gene ID: 9869, Accession: NP_036564.2, UniProt: Q15047 |
Catalog # | A300-121A |
Price | $433 |
Order / More Info | SETDB1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |