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Antigenic Specificity | JARID1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 250 µg/ml |
Applications | IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-JARID1B IHC Antibody, Affinity Purified. JARID1B (Jumonji AT-rich interactive domain 1B) is a member of the JARID 1 family of proteins that catalyze the demethylation of histones on lysine. The Jarid 1 family members include JARID1A, JARID1B, JARID1C and JARID1D. The members of this family possess a Jumonji C (JmjC) and Jumonji N (JmjN) domain as well as one ARID (AT-rich interactive domain) and three PHD-type zinc fingers. As histone demethylases, JARID 1 proteins function as transcriptional repressors. JARID1B expression is largely restricted to testis and may play a critical role in tumorigenesis as it has been found to be upregulated in prostate and breast cancer. |
Immunogen | Epitope: between 1494 and 1544 |
Other Names | PLU-1; retinoblastoma-binding protein 2 homolog 1; CT31; RBP2-H1; retinoblastoma-binding protein 2, homolog 1A; RBBP2H1A; putative DNA/chromatin binding motif; PUT1; protein phosphatase 1, regulatory subunit 98; PPP1R98; MRT65; lysine-specific demethylase 5B; lysine (K)-specific demethylase 5B; jumonji/ARID domain-containing protein 1B; jumonji, AT rich interactive domain 1B; histone demethylase JARID1B; cancer/testis antigen 31; JARID1B; PLU1 |
Gene, Accession # | Gene ID: 10765, Accession: NP_006609.3, UniProt: Q9UGL1 |
Catalog # | IHC-00370-T |
Price | $121 |
Order / More Info | JARID1B Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |