BRCC36 Antibody from FORTIS LIFE SCIENCES
Search, find, compare suppliers for anti-BRCC36 antibody, protein, ELISA kits.
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| Antigenic Specificity | BRCC36 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, (presumed: mouse, horse, porcine, panda, orangutan, monkey, white-tufted-ear marmoset, nine-banded armadillo, dusky titi monkey, crab-eating macaque, greater horseshoe bat, northern white-cheek |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 250 µg/ml |
| Applications | IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-BRCC36 IHC Antibody, Affinity Purified. BRCA1/BRCA2-containing complex subunit 36 (BRCC36) is a metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. BRCC36 is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites and leads to targeting of the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, BRCC36 specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX, antagonizing the RNF8-dependent ubiquitination at double-strand breaks (DSBs) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P46736]. |
| Immunogen | Epitope: between 266 and 316 |
| Other Names | C6.1A; BRCA1/BRCA2-containing complex subunit 36; lys-63-specific deubiquitinase BRCC36; CXorf53; BRCA1/BRCA2-containing complex subunit 3; BRCA1-A complex subunit BRCC36; BRCC36; BRISC complex subunit BRCC36 |
| Gene, Accession # | Gene ID: 79184, Accession: NP_077308.1, UniProt: P46736 |
| Catalog # | IHC-00715 |
| Price | $459 |
| Order / More Info | BRCC36 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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