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Antigenic Specificity | LYN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: rat) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-LYN Antibody, Affinity Purified. LYN is a tyrosine protein kinase that acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between proliferation and maturation. LYN acts as the mediator that relays suppressing signals from the chemokine receptor CXCR4 to beta-2 integrin LFA-1 in hematopoietic precursors. It is involved in induction of stress-activated protein kinase (SAPK), but not ERK or p38 MAPK, in response to genotoxic agents. LYN induces SAPK by a MKK7- and MEKK1-dependent mechanism [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P07948]. |
Immunogen | Epitope: between 1 and 50 |
Other Names | p56Lyn; tyrosine-protein kinase Lyn; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; JTK8; lck/Yes-related novel protein tyrosine kinase; p53Lyn |
Gene, Accession # | Gene ID: 4067, Accession: NP_002341.1, UniProt: P07948 |
Catalog # | A302-683A |
Price | $433 |
Order / More Info | LYN Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |