CNOT1 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | CNOT1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, (presumed: zebrafish, Xenopus tropicalis) |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-CNOT1 Antibody, Affinity Purified. Scaffolding component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Its scaffolding function implies its interaction with the catalytic complex module and diverse RNA-binding proteins mediating the complex recruitment to selected mRNA 3'UTRs. Involved in degradation of AU-rich element (ARE)-containing mRNAs probably via association with ZFP36. Mediates the recruitment of the CCR4-NOT complex to miRNA targets and to the RISC complex via association with TNRC6A, TNRC6B or TNRC6C. Acts as a transcriptional repressor. Represses the ligand-dependent transcriptional activation by nuclear receptors. Involved in the maintenance of emryonic stem (ES) cell identity. [taken from NCBI Entrez Gene (Gene ID: 23019)]. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/A5YKK6]. |
| Immunogen | Epitope: between 1400 and 1450 |
| Other Names | CDC39; NOT1H; NOT1 (negative regulator of transcription 1, yeast) homolog; NOT1; hNOT1; CCR4-NOT transcription complex subunit 1; CCR4-associated factor 1; adrenal gland protein AD-005; AD-005; negative regulator of transcription subunit 1 homolog |
| Gene, Accession # | Gene ID: 23019, Accession: NP_996882.1, UniProt: A5YKK6 |
| Catalog # | A305-787A |
| Price | $433 |
| Order / More Info | CNOT1 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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