PAN2/USP52 Antibody from FORTIS LIFE SCIENCES
Search, find, compare suppliers for anti-PAN2/USP52 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | PAN2/USP52 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, (presumed: rat) |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-PAN2/USP52 Antibody, Affinity Purified. PAB-dependent poly(A)-specific ribonuclease subunit PAN2 is the catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA when the poly(A) stretch is bound by poly(A)-binding protein (PABP), which is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q504Q3]. |
| Immunogen | Epitope: between 1 and 50 |
| Other Names | PAN2 polyA specific ribonuclease subunit; USP52; ubiquitin specific protease 52; ubiquitin specific peptidase 52; PAN2-PAN3 deadenylation complex catalytic subunit PAN2; PAN2 poly(A) specific ribonuclease subunit homolog; PAN deadenylation complex subunit 2; PABP-dependent poly(A) nuclease 2; PAB-dependent poly(A)-specific ribonuclease subunit PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2; PAB1P-dependent poly(A)-specific ribonuclease; PAB1P-dependent poly(A)-nuclease; inactive ubiquitin carboxyl-terminal hydrolase 52; PAN deadenylation complex catalytic subunit 2; poly(A)-nuclease deadenylation complex subunit 2 |
| Gene, Accession # | Gene ID: 9924, Accession: NP_055686.4, UniProt: Q504Q3 |
| Catalog # | A304-882A-T |
| Price | $121 |
| Order / More Info | PAN2/USP52 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
1440 Main Street, Suite 300
Waltham MA 02451
P: 800.338.9579
info@fortislife.com
https://www.fortislife.com
Profile of FORTIS LIFE SCIENCES
Return to Antibodies