Edit |   |
---|---|
Antigenic Specificity | NONO |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: mouse, rat, orangutan) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 200 µg/ml |
Applications | WB, IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-NONO Antibody, Affinity Purified. Non-POU-domain-containing octamer binding protein (NONO) is a member of the DBHS (drosophila behavior, human splicing) domain-containing family and is an RNA- and DNA- binding protein. NONO and other DBHS domain-containing proteins are multifunctional and are reported to be involved in transcriptional regulation, mRNA processing, and DNA non-homologous end joining (NHEJ). NONO functions as a coregulator of the androgen receptor (AR) and also regulates cAMP transcriptional activity by interacting with gene promoter elements. NONO is also involved in pre-mRNA splicing through an interaction with U5 snRNA and can stimulate DNA nonhomologous end joining (NHEJ) through the interaction with ku70/G22p and ku80/XRCC5 dimers. |
Immunogen | Epitope: between 1 and 50 |
Other Names | PPP1R114; protein phosphatase 1, regulatory subunit 114; P54NRB; p54(nrb); P54; NRB54; non-POU domain-containing octamer-binding protein; NonO protein; NMT55; MRXS34; DNA-binding p52/p100 complex, 52 kDa subunit; 54 kDa nuclear RNA- and DNA-binding protein; 55 kDa nuclear protein; non-POU domain-containing octamer (ATGCAAAT) binding protein |
Gene, Accession # | Gene ID: 4841, Accession: NP_031389.3, UniProt: Q15233 |
Catalog # | A300-582A-T |
Price | $121 |
Order / More Info | NONO Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |